OpenRx Open Medications Explorer
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Most reported to FAERS

Ranked by total U.S. adverse event reports mentioning the drug. 4,559 medications have at least one report.

4,559 medications · page 27 of 38

This is not a safety ranking. FAERS report counts track exposure, reporting behaviour and media attention as much as they track harm. A widely prescribed drug with a long market history will accumulate enormous totals. FDA's own position is that reports “do not prove that the drug caused the event”. See the methodology before drawing any conclusion.