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ToMORROW®

Cephapirin Benzathine

Veterinary NADA Approved 438 adverse event reports

Overview

Source: Animal Drugs @ FDA
Proprietary name
ToMORROW®
Active ingredient
Cephapirin Benzathine
Application type
NADA
Sponsor
Boehringer lngelheim Animal Health USA, Inc.
Applications on record
1
First published
August 12, 2024

Adverse event reports

Source: openFDA VeDDRA
438
Reports mentioning this ingredient
February 20, 1987 – February 20, 2026
58
Classified serious
per reporter assessment
33
Lack of expected efficacy
resistance signal
1
Human operator exposure
needle-stick or splash
Not a risk measure. Veterinary adverse event reports are influenced by how many animals are treated, reporting practice and product age. Reports do not establish that the product caused the event, and a single report can cover an entire herd or flock. Attribution here is by active ingredient because the source dataset redacts brand names.

Attributed by active ingredient “CEPHAPIRIN BENZATHINE”. Green Book ingredient names and VeDDRA ingredient names do not always agree exactly, so attribution is approximate and labelled as such.

Reported reactions

Source: openFDA VeDDRA

Clinical signs coded in the VICH VeDDRA four-level hierarchy, most frequent first.

Reaction terms reported for this ingredient, by report count.
Reaction (VeDDRA term) Reports Relative frequency
Residues in milk 136
Death 77
Mammary gland oedema 46
Tubes, Damaged 44
Tubes, Leaking 43
Mastitis NOS 38
Acute mastitis 24
Mammary gland disorder NOS 21
Alteration of milk quality 19
Lack of efficacy (bacteria) - NOS 19
Missing Cap 18
Product problem 18
Tubes, Abnormal 15
Fever 13
Caps, Abnormal 12
Containers, Damaged 10
Recumbency 9
Underfilling, Tubes 9
CULTURE/TITER DATA ABNORMAL 9
Abortion 8

Species affected

Source: openFDA VeDDRA
Cattle 288 Goat 4 Human 2 Horse 2 Sheep 1 Dog 1

Regulatory context

New Animal Drug Application (NADA). A pioneer approval evaluated for target animal safety, therapeutic effectiveness, manufacturing controls and — for food-producing species — human food safety including residue depletion.

Extra-label use in food-producing animals is governed by the Animal Medicinal Drug Use Clarification Act of 1994 (AMDUCA) and 21 CFR Part 530. It requires a valid veterinarian-client-patient relationship and is prohibited outright for certain drug classes. Withdrawal times are determined by FARAD, not by this index.

Sources for this page

Animal Drugs @ FDA FDA CVM Applications, sponsor, status, withdrawal
Animal & Veterinary Events FDA CVM VeDDRA adverse event aggregates by active ingredient