ToDAY® — veterinary medication

Overview

Source: Animal Drugs @ FDA

Proprietary name

ToDAY®

Active ingredient

Cephapirin Sodium

Application type

NADA

Sponsor

Boehringer lngelheim Animal Health USA, Inc.

Applications on record

1

First published

July 31, 2025

Adverse event reports

Source: openFDA VeDDRA

860

Reports mentioning this ingredient

January 29, 1987 – March 16, 2026

113

Classified serious

per reporter assessment

115

Lack of expected efficacy

resistance signal

3

Human operator exposure

needle-stick or splash

Not a risk measure. Veterinary adverse event reports are influenced by how many animals are treated, reporting practice and product age. Reports do not establish that the product caused the event, and a single report can cover an entire herd or flock. Attribution here is by active ingredient because the source dataset redacts brand names.

Attributed by active ingredient “CEPHAPIRIN SODIUM”. Green Book ingredient names and VeDDRA ingredient names do not always agree exactly, so attribution is approximate and labelled as such.

Reported reactions

Source: openFDA VeDDRA

Clinical signs coded in the VICH VeDDRA four-level hierarchy, most frequent first.

Reaction terms reported for this ingredient, by report count.
Reaction (VeDDRA term)	Reports	Relative frequency
Residues in milk	581
Drug dose administration interval too long	74
INEFFECTIVE, ANTIBIOTIC	51
Lack of efficacy (bacteria) - NOS	50
Tubes, Damaged	26
Tubes, Leaking	22
Tubes, Abnormal	20
Containers, Damaged	19
Product Defect, General	16
Product syringe issue	16
Lack of efficacy - NOS	12
Caps, Abnormal	11
Underfilling, Package	10
Dispenser, Abnormal	9
Product problem	9
Drug administration duration too long	9
Mastitis NOS	8
Uncoded sign	8
Syringe, Abnormal	8
Death	7

Species affected

Source: openFDA VeDDRA

Cattle 722 Goat 5 Horse 3 Human 1 Dog 1 Sheep 1

Regulatory context

New Animal Drug Application (NADA). A pioneer approval evaluated for target animal safety, therapeutic effectiveness, manufacturing controls and — for food-producing species — human food safety including residue depletion.

Extra-label use in food-producing animals is governed by the Animal Medicinal Drug Use Clarification Act of 1994 (AMDUCA) and 21 CFR Part 530. It requires a valid veterinarian-client-patient relationship and is prohibited outright for certain drug classes. Withdrawal times are determined by FARAD, not by this index.

Sources for this page

Animal Drugs @ FDA	FDA CVM	Applications, sponsor, status, withdrawal
Animal & Veterinary Events	FDA CVM	VeDDRA adverse event aggregates by active ingredient