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Metronidazole

Prescription ANDA TE AB Official labelling
Informational index, not medical advice. Content is reproduced from public FDA and NLM data. Always confirm against the manufacturer's current prescribing information. Report adverse events to FDA MedWatch.

Overview

Brand name
Metronidazole
Generic name
Metronidazole
Dosage form
Tablet
Route
Oral
Marketing category
ANDA · ANDA
Labeler
Bryant Ranch Prepack
Product type
Human Prescription Drug
DEA schedule
Not scheduled
Active ingredients
3
NDC product codes
74
Packages
264
Data completeness
83% of corroborating sources present

Active ingredients

Source: NDC Directory
Active ingredients and strengths as listed in the NDC Directory.
Ingredient Strength RxCUI Monograph
Metronidazole 125 mg/1 2702348 View
Metronidazole 250 mg/1 2702348 View
Metronidazole 500 mg/1 2702348 View

Forms, strengths and routes

Source: NDC Directory
Dosage form
Tablet
Route of administration
Oral
Presentations
338

Pharmacologic classes are listed in the class section below.

Pharmacologic class

Source: NDC Directory
Established pharmacologic classes (EPC), mechanisms of action (MoA), chemical structures (CS) and physiologic effects (PE).
Class Type Browse
Nitroimidazole Antimicrobial [EPC] EPC All 15 members
Nitroimidazoles [CS] CS All 15 members

Regulatory status

Source: Drugs@FDANDC Directory
Application number
206560
Application type
ANDA · Abbreviated New Drug Application
Approval date
November 16, 2016
Sponsor
CADILA
Products on application
2
Submissions recorded
7
Products approved under application 206560.
Product Trade name Form Strength Ingredient Status TE Flags
206560-001 METRONIDAZOLE TABLET METRONIDAZOLE Prescription AB
206560-002 METRONIDAZOLE TABLET METRONIDAZOLE Prescription AB

Therapeutic equivalence

Source: Orange Book
TE code
AB
Reference Listed Drug
No
Reference Standard
No

What this rating means: Therapeutically equivalent — bioequivalence demonstrated by in vivo or in vitro testing

Codes beginning with “A” indicate products the FDA considers therapeutically equivalent. Codes beginning with “B” indicate bioequivalence has not been established. See methodology.

Approval history

Source: Drugs@FDA
Most recent submissions on application 206560.
Type No. Action Status Date Review
Supplement 10 Labeling Approved November 5, 2024 Standard
Supplement 9 Labeling Approved July 8, 2024 Standard
Supplement 8 Labeling Approved June 18, 2024 Standard
Supplement 6 Labeling Approved August 15, 2023 Standard
Supplement 3 Labeling Approved August 19, 2021 Standard
Supplement 2 Labeling Approved August 13, 2019 Standard
Original application 1 Approved November 16, 2016 Standard

Prescribing information

Source: openFDA Drug Labeling

Reproduced verbatim from the Structured Product Labeling submitted to the FDA (effective 20260501). This is the manufacturer's labelling text, not a summary and not advice.

HUMAN PRESCRIPTION DRUG · 20260501 HUMAN PRESCRIPTION DRUG · 20260101 HUMAN PRESCRIPTION DRUG · 20260101 HUMAN PRESCRIPTION DRUG · 20251217

Boxed Warning

openFDA Drug Labeling

WARNING Metronidazole has been shown to be carcinogenic in mice and rats (see PRECAUTIONS ). Unnecessary use of the drug should be avoided. Its use should be reserved for the conditions described in the INDICATIONS AND USAGE section below.

Indications and Usage

openFDA Drug Labeling

INDICATIONS AND USAGE Symptomatic Trichomoniasis Metronidazole tablets, USP are indicated for the treatment of T. vaginalis infection in females and males when the presence of the trichomonad has been confirmed by appropriate laboratory procedures (wet smears and/or cultures). Asymptomatic Trichomoniasis Metronidazole tablets, USP are indicated in the treatment of asymptomatic T. vaginalis infection in females when the organism is associated with endocervicitis, cervicitis, or cervical erosion. Since there is evidence that presence of the trichomonad can interfere with accurate assessment of abnormal cytological smears, additional smears should be performed after eradication of the parasite. Treatment of Asymptomatic Sexual Partners T. vaginalis infection is a venereal disease. Therefore, asymptomatic sexual partners of treated patients should be treated simultaneously if the organism has been found to be present, in order to prevent reinfection of the partner. The decision as to whether to treat an asymptomatic male partner who has a negative culture or one for whom no culture has been attempted is an individual one. In making this decision, it should be noted that there is evidence that a woman may become reinfected if her sexual partner is not treated. Also, since there can be considerable difficulty in isolating the organism from the asymptomatic male carrier, negative smears and cultures cannot be relied upon in this regard. In any event, the sexual partner should be treated with metronidazole tablets, USP in cases of reinfection. Amebiasis Metronidazole tablets, USP are indicated in the treatment of acute intestinal amebiasis (amebic dysentery) and amebic liver abscess. In amebic liver abscess, metronidazole tablets, USP therapy does not obviate the need for aspiration or drainage of pus. Anaerobic Bacterial Infections Metronidazole tablets, USP are indicated in the treatment of serious infections caused by susceptible anaerobic bacteria. Indicated surgical procedures should be performed in conjunction with metronidazole tablets, USP therapy. In a mixed aerobic and anaerobic infection, antimicrobials appropriate for the treatment of the aerobic infection should be used in addition to metronidazole tablets, USP. INTRA-ABDOMINAL INFECTIONS, including peritonitis, intra-abdominal abscess, and liver abscess, caused by Bacteroides species including the B. fragilis group (B. fragilis , B. distasonis , B. ovatus , B. thetaiotaomicron , B. vulgatus ), Clostridium species , Eubacterium species, Peptococcus species , and Peptostreptococcus species. SKIN AND SKIN STRUCTURE INFECTIONS caused by Bacteroides species including the B. fragilis group, Clostridium species, Peptococcus species, Peptostreptococcus species, and Fusobacterium species. GYNECOLOGIC INFECTIONS, including endometritis, endomyometritis, tubo-ovarian abscess, and postsurgical vaginal cuff infection, caused by Bacteroides species including the B. fragilis group, Clostridium species, Peptococcus species, Peptostreptococcus species, and Fusobacterium species. BACTERIAL SEPTICEMIA caused by Bacteroides species including the B. fragilis group and Clostridium species. BONE AND JOINT INFECTIONS, (as adjunctive therapy), caused by Bacteroides species including the B. fragilis group. CENTRAL NERVOUS SYSTEM (CNS) INFECTIONS, including meningitis and brain abscess, caused by Bacteroides species including the B. fragilis group. LOWER RESPIRATORY TRACT INFECTIONS, including pneumonia, empyema, and lung abscess, caused by Bacteroides species including the B. fragilis group. ENDOCARDITIS caused by Bacteroides species including the B. fragilis group. To reduce the development of drug-resistant bacteria and maintain the effectiveness of metronidazole tablets, USP and other antibacterial drugs, metronidazole tablets, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility infor …

Dosage and Administration

openFDA Drug Labeling

DOSAGE AND ADMINISTRATION Trichomoniasis: In the Female: One-day treatment − two grams of metronidazole tablets, given either as a single dose or in two divided doses of one gram each, given in the same day. Seven-day course of treatment - 250 mg three times daily for seven consecutive days. There is some indication from controlled comparative studies that cure rates as determined by vaginal smears and signs and symptoms, may be higher after a seven-day course of treatment than after a one-day treatment regimen. The dosage regimen should be individualized. Single-dose treatment can assure compliance, especially if administered under supervision, in those patients who cannot be relied on to continue the seven-day regimen. A seven-day course of treatment may minimize reinfection by protecting the patient long enough for the sexual contacts to obtain appropriate treatment. Further, some patients may tolerate one treatment regimen better than the other. Pregnant patients should not be treated during the first trimester (see CONTRAINDICATIONS ). In pregnant patients for whom alternative treatment has been inadequate, the one-day course of therapy should not be used, as it results in higher serum levels which can reach the fetal circulation (see PRECAUTIONS , Pregnancy ). When repeat courses of the drug are required, it is recommended that an interval of four to six weeks elapse between courses and that the presence of the trichomonad be reconfirmed by appropriate laboratory measures. Total and differential leukocyte counts should be made before and after re-treatment. In the Male: Treatment should be individualized as it is for the female. Amebiasis Adults: For acute intestinal amebiasis (acute amebic dysentery): 750 mg orally three times daily for 5 to 10 days. For amebic liver abscess: 500 mg or 750 mg orally three times daily for 5 to 10 days. Pediatric patients: 35 to 50 mg/kg/24 hours, divided into three doses, orally for 10 days. Anaerobic Bacterial Infections In the treatment of most serious anaerobic infections, intravenous metronidazole is usually administered initially. The usual adult oral dosage is 7.5 mg/kg every six hours (approx. 500 mg for a 70-kg adult). A maximum of 4 g should not be exceeded during a 24-hour period. The usual duration of therapy is 7 to 10 days; however, infections of the bone and joint, lower respiratory tract, and endocardium may require longer treatment. Dosage Adjustments Patients with Severe Hepatic Impairment For patients with severe hepatic impairment (Child-Pugh C), the dose of metronidazole tablets should be reduced by 50% (see CLINICAL PHARMACOLOGY and PRECAUTIONS ). Patients Undergoing Hemodialysis: Hemodialysis removes significant amounts of metronidazole and its metabolites from systemic circulation. The clearance of metronidazole will depend on the type of dialysis membrane used, the duration of the dialysis session, and other factors. If the administration of metronidazole cannot be separated from the hemodialysis session, supplementation of metronidazole dosage following the hemodialysis session should be considered, depending on the patient’s clinical situation (see CLINICAL PHARMACOLOGY ).

Dosage Adjustments Patients with Severe Hepatic Impairment For patients with severe hepatic impairment (Child-Pugh C), the dose of metronidazole tablets should be reduced by 50% (see CLINICAL PHARMACOLOGY and PRECAUTIONS ). Patients Undergoing Hemodialysis: Hemodialysis removes significant amounts of metronidazole and its metabolites from systemic circulation. The clearance of metronidazole will depend on the type of dialysis membrane used, the duration of the dialysis session, and other factors. If the administration of metronidazole cannot be separated from the hemodialysis session, supplementation of metronidazole dosage following the hemodialysis session should be considered, depending on the patient’s clinical situation (see CLINICAL PHARMACOLOGY ).

Contraindications

openFDA Drug Labeling

CONTRAINDICATIONS Hypersensitivity Metronidazole tablets are contraindicated in patients with a prior history of hypersensitivity to metronidazole or other nitroimidazole derivatives. In patients with trichomoniasis, metronidazole tablets are contraindicated during the first trimester of pregnancy (see PRECAUTIONS ). Psychotic Reaction with Disulfiram Use of oral metronidazole is associated with psychotic reactions in alcoholic patients who were using disulfiram concurrently. Do not administer metronidazole to patients who have taken disulfiram within the last two weeks (see PRECAUTIONS , Drug Interactions ). Interaction with Alcohol Use of oral metronidazole is associated with a disulfiram-like reaction to alcohol, including abdominal cramps, nausea, vomiting, headaches, and flushing. Discontinue consumption of alcohol or products containing propylene glycol during and for at least three days after therapy with metronidazole (see PRECAUTIONS , Drug Interactions ). Cockayne Syndrome Metronidazole Tablets are contraindicated in patients with Cockayne syndrome. Severe irreversible hepatotoxicity/acute liver failure with fatal outcomes have been reported after initiation of metronidazole in patients with Cockayne syndrome (see ADVERSE REACTIONS ).

Hypersensitivity Metronidazole tablets are contraindicated in patients with a prior history of hypersensitivity to metronidazole or other nitroimidazole derivatives. In patients with trichomoniasis, metronidazole tablets are contraindicated during the first trimester of pregnancy (see PRECAUTIONS ).

Psychotic Reaction with Disulfiram Use of oral metronidazole is associated with psychotic reactions in alcoholic patients who were using disulfiram concurrently. Do not administer metronidazole to patients who have taken disulfiram within the last two weeks (see PRECAUTIONS , Drug Interactions ).

Interaction with Alcohol Use of oral metronidazole is associated with a disulfiram-like reaction to alcohol, including abdominal cramps, nausea, vomiting, headaches, and flushing. Discontinue consumption of alcohol or products containing propylene glycol during and for at least three days after therapy with metronidazole (see PRECAUTIONS , Drug Interactions ). Cockayne Syndrome Metronidazole Tablets are contraindicated in patients with Cockayne syndrome. Severe irreversible hepatotoxicity/acute liver failure with fatal outcomes have been reported after initiation of metronidazole in patients with Cockayne syndrome (see ADVERSE REACTIONS ).

WARNINGS Central and Peripheral Nervous System Effects Encephalopathy and peripheral neuropathy: Cases of encephalopathy and peripheral neuropathy (including optic neuropathy) have been reported with metronidazole. Encephalopathy has been reported in association with cerebellar toxicity characterized by ataxia, dizziness, and dysarthria. CNS lesions seen on MRI have been described in reports of encephalopathy. CNS symptoms are generally reversible within days to weeks upon discontinuation of metronidazole. CNS lesions seen on MRI have also been described as reversible. Peripheral neuropathy, mainly of sensory type has been reported and is characterized by numbness or paresthesia of an extremity. Convulsive seizures have been reported in patients treated with metronidazole. Aseptic meningitis: Cases of aseptic meningitis have been reported with metronidazole. Symptoms can occur within hours of dose administration and generally resolve after metronidazole therapy is discontinued. The appearance of abnormal neurologic signs and symptoms demands the prompt evaluation of the benefit/risk ratio of the continuation of therapy (see ADVERSE REACTIONS). Risk of Hepatotoxicity and Death in Patients with Cockayne Syndrome Cases of severe hepatotoxicity/acute hepatic failure, including cases with a fatal outcome with very rapid onset after treatment initiation in patients with Cockayne syndrome have been reported with products containing metronidazole for systemic use. In this population, metronidazole should therefore be used after careful benefit-risk assessment and only if no alternative treatment is available. Obtain liver function tests prior to the start of therapy, within the first 2-3 days after initiation of therapy, frequently during therapy and after end of treatment. Discontinue metronidazole if elevation of liver function tests occurs, and monitor liver function tests until the baseline values are reached. Advise patients with Cockayne syndrome to stop taking metronidazole immediately if they experience any symptoms of potential liver injury, such as abdominal pain, nausea, change in stool color or jaundice, and to contact their healthcare provider.

Central and Peripheral Nervous System Effects Encephalopathy and peripheral neuropathy: Cases of encephalopathy and peripheral neuropathy (including optic neuropathy) have been reported with metronidazole. Encephalopathy has been reported in association with cerebellar toxicity characterized by ataxia, dizziness, and dysarthria. CNS lesions seen on MRI have been described in reports of encephalopathy. CNS symptoms are generally reversible within days to weeks upon discontinuation of metronidazole. CNS lesions seen on MRI have also been described as reversible. Peripheral neuropathy, mainly of sensory type has been reported and is characterized by numbness or paresthesia of an extremity. Convulsive seizures have been reported in patients treated with metronidazole. Aseptic meningitis: Cases of aseptic meningitis have been reported with metronidazole. Symptoms can occur within hours of dose administration and generally resolve after metronidazole therapy is discontinued. The appearance of abnormal neurologic signs and symptoms demands the prompt evaluation of the benefit/risk ratio of the continuation of therapy (see ADVERSE REACTIONS).

Risk of Hepatotoxicity and Death in Patients with Cockayne Syndrome Cases of severe hepatotoxicity/acute hepatic failure, including cases with a fatal outcome with very rapid onset after treatment initiation in patients with Cockayne syndrome have been reported with products containing metronidazole for systemic use. In this population, metronidazole should therefore be used after careful benefit-risk assessment and only if no alternative treatment is available. Obtain liver function tests prior to the start of therapy, within the first 2-3 days after initiation of therapy, frequently during therapy and after end of treatment. Discontinue metronidaz …

Adverse Reactions

openFDA Drug Labeling

ADVERSE REACTIONS The following reactions have been reported during treatment with metronidazole: Central Nervous System: The most serious adverse reactions reported in patients treated with metronidazole have been convulsive seizures, encephalopathy, aseptic meningitis, optic and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity. Since persistent peripheral neuropathy has been reported in some patients receiving prolonged administration of metronidazole, patients should be specifically warned about these reactions and should be told to stop the drug and report immediately to their physicians if any neurologic symptoms occur. In addition, patients have reported headache, syncope, dizziness, vertigo, incoordination, ataxia, tinnitus, hearing impairment, hearing loss, confusion, dysarthria, irritability, depression, weakness, and insomnia (see WARNINGS ). Gastrointestinal: The most common adverse reactions reported have been referable to the gastrointestinal tract, particularly nausea, sometimes accompanied by headache, anorexia, and occasionally vomiting; diarrhea; epigastric distress; and abdominal cramping and constipation. Mouth : A sharp, unpleasant metallic taste is not unusual. Furry tongue, glossitis, and stomatitis have occurred; these may be associated with a sudden overgrowth of Candida which may occur during therapy. Dermatologic: Dermatitis bullous, fixed drug eruption, erythematous rash and pruritus. Hematopoietic : Reversible neutropenia (leukopenia); rarely, reversible thrombocytopenia. Cardiovascular : QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. Flattening of the T-wave may be seen in electrocardiographic tracings. Hypersensitivity : Toxic epidermal necrolysis (TEN), Stevens-Johnson Syndrome (SJS), drug reaction with eosinophilia and systemic symptoms (DRESS), acute generalized exanthematous pustulosis (AGEP) (see WARNINGS ), urticaria, erythematous rash, flushing, nasal congestion, dryness of the mouth (or vagina or vulva), and fever. Renal : Dysuria, cystitis, polyuria, incontinence, and a sense of pelvic pressure. Instances of darkened urine have been reported by approximately one patient in 100,000. Although the pigment which is probably responsible for this phenomenon has not been positively identified, it is almost certainly a metabolite of metronidazole and seems to have no clinical significance. Hepatic : Cases of severe irreversible hepatotoxicity/acute liver failure, including cases with fatal outcomes with very rapid onset after initiation of systemic use of metronidazole, have been reported in patients with Cockayne syndrome (latency from drug start to signs of liver failure as short as 2 days) (see CONTRAINDICATIONS ). Other : Proliferation of Candida in the vagina, dyspareunia, decrease of libido, proctitis, and fleeting joint pains sometimes resembling “serum sickness.” Rare cases of pancreatitis, which generally abated on withdrawal of the drug, have been reported. Patients with Crohn’s disease are known to have an increased incidence of gastrointestinal and certain extraintestinal cancers. There have been some reports in the medical literature of breast and colon cancer in Crohn’s disease patients who have been treated with metronidazole at high doses for extended periods of time. A cause and effect relationship has not been established. Crohn’s disease is not an approved indication for metronidazole tablets. To report SUSPECTED ADVERSE REACTIONS, contact Avet Pharmaceuticals Inc. at 1-866-901-DRUG (3784) or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch

Drug Interactions

openFDA Drug Labeling

Drug Interactions Disulfiram Psychotic reactions have been reported in alcoholic patients who are using metronidazole and disulfiram concurrently. Metronidazole should not be given to patients who have taken disulfiram within the last two weeks (see CONTRAINDICATIONS ). Alcoholic Beverages Abdominal cramps, nausea, vomiting, headaches, and flushing may occur if alcoholic beverages or products containing propylene glycol are consumed during or following metronidazole therapy (see CONTRAINDICATIONS ). Warfarin and other Oral Anticoagulants Metronidazole has been reported to potentiate the anticoagulant effect of warfarin and other oral coumarin anticoagulants, resulting in a prolongation of prothrombin time. When metronidazole is prescribed for patients on this type of anticoagulant therapy, prothrombin time and INR should be carefully monitored. Lithium In patients stabilized on relatively high doses of lithium, short-term metronidazole therapy has been associated with elevation of serum lithium and, in a few cases, signs of lithium toxicity. Serum lithium and serum creatinine levels should be obtained several days after beginning metronidazole to detect any increase that may precede clinical symptoms of lithium intoxication. Busulfan Metronidazole has been reported to increase plasma concentrations of busulfan, which can result in an increased risk for serious busulfan toxicity. Metronidazole should not be administered concomitantly with busulfan unless the benefit outweighs the risk. If no therapeutic alternatives to metronidazole are available, and concomitant administration with busulfan is medically needed, frequent monitoring of busulfan plasma concentration should be performed and the busulfan dose should be adjusted accordingly. Drugs that Inhibit CYP450 Enzymes The simultaneous administration of drugs that decrease microsomal liver enzyme activity, such as cimetidine, may prolong the half-life and decrease plasma clearance of metronidazole. Drugs that Induce CYP450 Enzymes The simultaneous administration of drugs that induce microsomal liver enzymes, such as phenytoin or phenobarbital, may accelerate the elimination of metronidazole, resulting in reduced plasma levels; impaired clearance of phenytoin has also been reported. Drugs that Prolong the QT interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval.

Disulfiram Psychotic reactions have been reported in alcoholic patients who are using metronidazole and disulfiram concurrently. Metronidazole should not be given to patients who have taken disulfiram within the last two weeks (see CONTRAINDICATIONS ).

Alcoholic Beverages Abdominal cramps, nausea, vomiting, headaches, and flushing may occur if alcoholic beverages or products containing propylene glycol are consumed during or following metronidazole therapy (see CONTRAINDICATIONS ).

Warfarin and other Oral Anticoagulants Metronidazole has been reported to potentiate the anticoagulant effect of warfarin and other oral coumarin anticoagulants, resulting in a prolongation of prothrombin time. When metronidazole is prescribed for patients on this type of anticoagulant therapy, prothrombin time and INR should be carefully monitored.

Lithium In patients stabilized on relatively high doses of lithium, short-term metronidazole therapy has been associated with elevation of serum lithium and, in a few cases, signs of lithium toxicity. Serum lithium and serum creatinine levels should be obtained several days after beginning metronidazole to detect any increase that may precede clinical symptoms of lithium intoxication.

Busulfan Metronidazole has been reported to increase plasma concentrations of busulfan, which can result in an increased risk for serious busulfan toxicity. Metronidazole should not be administered concomitantly with busulfan unless the benefit outweighs the risk. If no therapeutic alternatives to metronidazole ar …

Description

openFDA Drug Labeling

DESCRIPTION Metronidazole tablets, 250 mg or 500 mg is an oral formulation of the synthetic nitroimidazole antimicrobial, 2-methyl-5-nitro-1H-imidazole-1-ethanol, which has the following structural formula: Metronidazole USP is a white to pale yellow, crystalline powder. It is sparingly soluble in water and alcohol; slightly soluble in ether and chloroform; soluble in dilute hydrochloric acid. Each metronidazole tablet, USP intended for oral administration contains 250 mg or 500 mg of metronidazole. In addition, each tablet contains the following inactive ingredients: colloidal silicon dioxide, hypromellose, low-substituted hydroxypropyl cellulose, microcrystalline cellulose and stearic acid. Additionally, each tablet contains opadry II white 02F580003 which contains hypromellose, polyethylene glycol, talc and titanium dioxide. figure

OVERDOSAGE Single oral doses of metronidazole, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral metronidazole has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day. Treatment of Overdosage : There is no specific antidote for metronidazole overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.

How Supplied / Storage and Handling

openFDA Drug Labeling

HOW SUPPLIED Metronidazole Tablets USP, 250 mg are white to off-white, round, biconvex, film coated tablets debossed with '850' on one side and plain on other side and are supplied as follows: NDC 76420-800-21 in bottles of 21 tablets (repackaged from NDC 72578-007-XX) NDC 76420-800-30 in bottles of 30 tablets (repackaged from NDC 72578-007-XX) NDC 76420-800-60 in bottles of 60 tablets (repackaged from NDC 72578-007-XX) NDC 76420-800-90 in bottles of 90 tablets (repackaged from NDC 72578-007-XX) NDC 76420-800-01 in bottles of 100 tablets (relabeled from NDC 72578-007-01) NDC 76420-800-25 in bottles of 250 tablets (relabeled from NDC 72578-007-21) NDC 76420-800-05 in bottles of 500 tablets (relabeled from NDC 72578-007-05) Metronidazole Tablets USP, 500 mg are white to off-white, oval shaped, biconvex, film coated tablets debossed with '851' on one side and plain on other side and are supplied as follows: NDC 76420-801-21 in bottles of 21 tablets (repackaged from NDC 72578-008-XX) NDC 76420-801-30 in bottles of 30 tablets (repackaged from NDC 72578-008-XX) NDC 76420-801-60 in bottles of 60 tablets (repackaged from NDC 72578-008-XX) NDC 76420-801-90 in bottles of 90 tablets (repackaged from NDC 72578-008-XX) NDC 76420-801-50 in bottles of 50 tablets (relabeled from NDC 72578-008-18) NDC 76420-801-01 in bottles of 100 tablets (relabeled from NDC 72578-008-01) NDC 76420-801-05 in bottles of 500 tablets (relabeled from NDC 72578-008-05) Storage Store at 20° to 25°C (68° to 77°F) [See USP Controlled Room Temperature] . Protect from light. Dispense in a tight, light-resistant container (USP). Relabeled and Repackaged by: Enovachem PHARMACEUTICALS Torrance, CA 90501

Adverse event reports

Source: openFDA FAERS
64,630
FAERS reports mentioning this drug
as of 2026-09-25T03:42:24+00:00
A report count is not a risk measure. FAERS accepts voluntary and mandatory reports without establishing causation, and reporting is influenced by how widely a drug is used, how long it has been marketed, and media attention. FDA states that reports “do not prove that the drug caused the event”. Compare rates, not totals.

Attributed to this product's most-reported active ingredient: METRONIDAZOLE. Combination products with more than six active ingredients are not attributed, because a report count summed across a long ingredient list measures the list, not the medicine.

Shortages

Source: FDA Drug Shortages
Availability records from the FDA Drug Shortages database.
Status Availability Company Presentation Updated
Current Available Baxter Healthcare Flagyl I.v. Rtu In Plastic Container, Injection, 500 mg/100 mL (NDC 0338-1055-48) September 17, 2026
Current Limited Availability InfoRLife SA Metronidazole in Flexible Container, Injection, 500 mg/100 mL (NDC 0409-0152-24) August 18, 2026
Current Limited Availability InfoRLife SA Metronidazole, Injection, 500 mg/100 mL (NDC 25021-131-82) August 18, 2026
Current Unavailable Gland Pharma Limited Metronidazole In Plastic Container, Injection, 500 mg/100 mL (NDC 47335-993-01) July 22, 2026

Packaging and NDCs

Source: NDC Directory
Every National Drug Code package associated with this medication. The NDC is the identifier used for dispensing, billing and pharmacovigilance in the United States.
Package NDC Product NDC Labeler Description Marketing start
50090-5691-0 50090-5691 A-S Medication Solutions 21 TABLET in 1 BOTTLE (50090-5691-0) September 21, 2021
50090-5691-1 50090-5691 A-S Medication Solutions 28 TABLET in 1 BOTTLE (50090-5691-1) September 21, 2021
50090-5691-2 50090-5691 A-S Medication Solutions 30 TABLET in 1 BOTTLE (50090-5691-2) September 21, 2021
69292-207-01 69292-207 AMICI PHARMA INC 100 TABLET in 1 BOTTLE (69292-207-01) August 26, 2019
69292-207-50 69292-207 AMICI PHARMA INC 500 TABLET in 1 BOTTLE (69292-207-50) August 26, 2019
69292-208-01 69292-208 AMICI PHARMA INC 100 TABLET in 1 BOTTLE (69292-208-01) November 22, 2019
69292-208-50 69292-208 AMICI PHARMA INC 500 TABLET in 1 BOTTLE (69292-208-50) November 22, 2019
15955-388-01 15955-388 Alembic Labs LLC 100 TABLET in 1 BOTTLE (15955-388-01) June 26, 2019
15955-388-05 15955-388 Alembic Labs LLC 500 TABLET in 1 BOTTLE (15955-388-05) June 26, 2019
15955-389-01 15955-389 Alembic Labs LLC 100 TABLET in 1 BOTTLE (15955-389-01) June 26, 2019
15955-389-05 15955-389 Alembic Labs LLC 500 TABLET in 1 BOTTLE (15955-389-05) June 26, 2019
62332-016-30 62332-016 Alembic Pharmaceuticals Inc. 30 TABLET in 1 BOTTLE (62332-016-30) December 1, 2016
62332-016-31 62332-016 Alembic Pharmaceuticals Inc. 100 TABLET in 1 BOTTLE (62332-016-31) December 1, 2016
62332-016-50 62332-016 Alembic Pharmaceuticals Inc. 50 TABLET in 1 BOTTLE (62332-016-50) December 1, 2016
62332-016-61 62332-016 Alembic Pharmaceuticals Inc. 250 TABLET in 1 BOTTLE (62332-016-61) December 1, 2016
62332-016-71 62332-016 Alembic Pharmaceuticals Inc. 500 TABLET in 1 BOTTLE (62332-016-71) December 1, 2016
62332-016-91 62332-016 Alembic Pharmaceuticals Inc. 1000 TABLET in 1 BOTTLE (62332-016-91) December 1, 2016
62332-017-30 62332-017 Alembic Pharmaceuticals Inc. 30 TABLET in 1 BOTTLE (62332-017-30) December 1, 2016
62332-017-31 62332-017 Alembic Pharmaceuticals Inc. 100 TABLET in 1 BOTTLE (62332-017-31) December 1, 2016
62332-017-50 62332-017 Alembic Pharmaceuticals Inc. 50 TABLET in 1 BOTTLE (62332-017-50) December 1, 2016
62332-017-71 62332-017 Alembic Pharmaceuticals Inc. 500 TABLET in 1 BOTTLE (62332-017-71) December 1, 2016
62332-017-91 62332-017 Alembic Pharmaceuticals Inc. 1000 TABLET in 1 BOTTLE (62332-017-91) December 1, 2016
46708-428-30 46708-428 Alembic Pharmaceuticals Limited 30 TABLET in 1 BOTTLE (46708-428-30) December 1, 2016
46708-428-31 46708-428 Alembic Pharmaceuticals Limited 100 TABLET in 1 BOTTLE (46708-428-31) December 1, 2016
46708-428-50 46708-428 Alembic Pharmaceuticals Limited 50 TABLET in 1 BOTTLE (46708-428-50) December 1, 2016
46708-428-61 46708-428 Alembic Pharmaceuticals Limited 250 TABLET in 1 BOTTLE (46708-428-61) December 1, 2016
46708-428-71 46708-428 Alembic Pharmaceuticals Limited 500 TABLET in 1 BOTTLE (46708-428-71) December 1, 2016
46708-428-91 46708-428 Alembic Pharmaceuticals Limited 1000 TABLET in 1 BOTTLE (46708-428-91) December 1, 2016
46708-429-30 46708-429 Alembic Pharmaceuticals Limited 30 TABLET in 1 BOTTLE (46708-429-30) December 1, 2016
46708-429-31 46708-429 Alembic Pharmaceuticals Limited 100 TABLET in 1 BOTTLE (46708-429-31) December 1, 2016
46708-429-50 46708-429 Alembic Pharmaceuticals Limited 50 TABLET in 1 BOTTLE (46708-429-50) December 1, 2016
46708-429-71 46708-429 Alembic Pharmaceuticals Limited 500 TABLET in 1 BOTTLE (46708-429-71) December 1, 2016
46708-429-91 46708-429 Alembic Pharmaceuticals Limited 1000 TABLET in 1 BOTTLE (46708-429-91) December 1, 2016
60687-526-01 60687-526 American Health Packaging 100 BLISTER PACK in 1 BOX, UNIT-DOSE (60687-526-01) / 1 TABLET in 1 BLISTER PACK (60687-526-11) April 9, 2020
60687-550-01 60687-550 American Health Packaging 100 BLISTER PACK in 1 BOX, UNIT-DOSE (60687-550-01) / 1 TABLET in 1 BLISTER PACK (60687-550-11) March 20, 2020
76420-800-01 76420-800 Asclemed USA, Inc. 100 TABLET in 1 BOTTLE (76420-800-01) April 26, 2024
76420-800-05 76420-800 Asclemed USA, Inc. 500 TABLET in 1 BOTTLE (76420-800-05) April 26, 2024
76420-800-21 76420-800 Asclemed USA, Inc. 21 TABLET in 1 BOTTLE (76420-800-21) April 26, 2024
76420-800-25 76420-800 Asclemed USA, Inc. 250 TABLET in 1 BOTTLE (76420-800-25) April 26, 2024
76420-800-30 76420-800 Asclemed USA, Inc. 30 TABLET in 1 BOTTLE (76420-800-30) April 26, 2024
76420-800-60 76420-800 Asclemed USA, Inc. 60 TABLET in 1 BOTTLE (76420-800-60) April 26, 2024
76420-800-90 76420-800 Asclemed USA, Inc. 90 TABLET in 1 BOTTLE (76420-800-90) April 26, 2024
76420-801-01 76420-801 Asclemed USA, Inc. 100 TABLET in 1 BOTTLE (76420-801-01) April 26, 2024
76420-801-05 76420-801 Asclemed USA, Inc. 500 TABLET in 1 BOTTLE (76420-801-05) April 26, 2024
76420-801-21 76420-801 Asclemed USA, Inc. 21 TABLET in 1 BOTTLE (76420-801-21) April 26, 2024
76420-801-30 76420-801 Asclemed USA, Inc. 30 TABLET in 1 BOTTLE (76420-801-30) April 26, 2024
76420-801-50 76420-801 Asclemed USA, Inc. 50 TABLET in 1 BOTTLE (76420-801-50) April 26, 2024
76420-801-60 76420-801 Asclemed USA, Inc. 60 TABLET in 1 BOTTLE (76420-801-60) April 26, 2024
76420-801-90 76420-801 Asclemed USA, Inc. 90 TABLET in 1 BOTTLE (76420-801-90) April 26, 2024
65862-694-01 65862-694 Aurobindo Pharma Limited 100 TABLET in 1 BOTTLE (65862-694-01) May 29, 2015
65862-694-05 65862-694 Aurobindo Pharma Limited 500 TABLET in 1 BOTTLE (65862-694-05) May 29, 2015
65862-694-25 65862-694 Aurobindo Pharma Limited 250 TABLET in 1 BOTTLE (65862-694-25) May 29, 2015
65862-694-50 65862-694 Aurobindo Pharma Limited 50 TABLET in 1 BOTTLE (65862-694-50) May 29, 2015
65862-694-99 65862-694 Aurobindo Pharma Limited 1000 TABLET in 1 BOTTLE (65862-694-99) May 29, 2015
65862-695-01 65862-695 Aurobindo Pharma Limited 100 TABLET in 1 BOTTLE (65862-695-01) May 29, 2015
65862-695-05 65862-695 Aurobindo Pharma Limited 500 TABLET in 1 BOTTLE (65862-695-05) May 29, 2015
65862-695-50 65862-695 Aurobindo Pharma Limited 50 TABLET in 1 BOTTLE (65862-695-50) May 29, 2015
65862-695-99 65862-695 Aurobindo Pharma Limited 1000 TABLET in 1 BOTTLE (65862-695-99) May 29, 2015
50268-534-15 50268-534 AvPAK 50 BLISTER PACK in 1 BOX (50268-534-15) / 1 TABLET in 1 BLISTER PACK (50268-534-11) October 30, 2019
50268-535-15 50268-535 AvPAK 50 BLISTER PACK in 1 BOX (50268-535-15) / 1 TABLET in 1 BLISTER PACK (50268-535-11) October 30, 2019
63629-1386-0 63629-1386 Bryant Ranch Prepack 40 TABLET in 1 BOTTLE (63629-1386-0) August 3, 2010
63629-1386-1 63629-1386 Bryant Ranch Prepack 20 TABLET in 1 BOTTLE (63629-1386-1) December 16, 2004
63629-1386-2 63629-1386 Bryant Ranch Prepack 30 TABLET in 1 BOTTLE (63629-1386-2) December 20, 2004
63629-1386-3 63629-1386 Bryant Ranch Prepack 14 TABLET in 1 BOTTLE (63629-1386-3) March 26, 2007
63629-1386-4 63629-1386 Bryant Ranch Prepack 56 TABLET in 1 BOTTLE (63629-1386-4) August 10, 2006
63629-1386-5 63629-1386 Bryant Ranch Prepack 21 TABLET in 1 BOTTLE (63629-1386-5) February 12, 2009
63629-1386-6 63629-1386 Bryant Ranch Prepack 4 TABLET in 1 BOTTLE (63629-1386-6) June 12, 2008
63629-1386-7 63629-1386 Bryant Ranch Prepack 28 TABLET in 1 BOTTLE (63629-1386-7) July 7, 2008
63629-1386-8 63629-1386 Bryant Ranch Prepack 100 TABLET in 1 BOTTLE (63629-1386-8) August 26, 2010
63629-1386-9 63629-1386 Bryant Ranch Prepack 60 TABLET in 1 BOTTLE (63629-1386-9) March 8, 2022
71335-0858-0 71335-0858 Bryant Ranch Prepack 7 TABLET in 1 BOTTLE (71335-0858-0) August 9, 2024
71335-0858-1 71335-0858 Bryant Ranch Prepack 21 TABLET in 1 BOTTLE (71335-0858-1) May 13, 2019
71335-0858-2 71335-0858 Bryant Ranch Prepack 30 TABLET in 1 BOTTLE (71335-0858-2) December 26, 2019
71335-0858-3 71335-0858 Bryant Ranch Prepack 20 TABLET in 1 BOTTLE (71335-0858-3) August 9, 2024
71335-0858-4 71335-0858 Bryant Ranch Prepack 60 TABLET in 1 BOTTLE (71335-0858-4) August 9, 2024
71335-0858-5 71335-0858 Bryant Ranch Prepack 28 TABLET in 1 BOTTLE (71335-0858-5) August 9, 2024
71335-0858-6 71335-0858 Bryant Ranch Prepack 14 TABLET in 1 BOTTLE (71335-0858-6) August 9, 2024
71335-0858-7 71335-0858 Bryant Ranch Prepack 40 TABLET in 1 BOTTLE (71335-0858-7) August 9, 2024
71335-0858-8 71335-0858 Bryant Ranch Prepack 42 TABLET in 1 BOTTLE (71335-0858-8) August 9, 2024
71335-0858-9 71335-0858 Bryant Ranch Prepack 56 TABLET in 1 BOTTLE (71335-0858-9) August 6, 2018
71335-1681-0 71335-1681 Bryant Ranch Prepack 40 TABLET in 1 BOTTLE (71335-1681-0) October 31, 2024
71335-1681-1 71335-1681 Bryant Ranch Prepack 20 TABLET in 1 BOTTLE (71335-1681-1) August 5, 2020
71335-1681-2 71335-1681 Bryant Ranch Prepack 30 TABLET in 1 BOTTLE (71335-1681-2) August 4, 2020
71335-1681-3 71335-1681 Bryant Ranch Prepack 14 TABLET in 1 BOTTLE (71335-1681-3) August 5, 2020
71335-1681-4 71335-1681 Bryant Ranch Prepack 56 TABLET in 1 BOTTLE (71335-1681-4) October 31, 2024
71335-1681-5 71335-1681 Bryant Ranch Prepack 21 TABLET in 1 BOTTLE (71335-1681-5) August 10, 2020
71335-1681-6 71335-1681 Bryant Ranch Prepack 4 TABLET in 1 BOTTLE (71335-1681-6) July 12, 2021
71335-1681-7 71335-1681 Bryant Ranch Prepack 28 TABLET in 1 BOTTLE (71335-1681-7) August 31, 2020
71335-1681-8 71335-1681 Bryant Ranch Prepack 100 TABLET in 1 BOTTLE (71335-1681-8) October 31, 2024
71335-1681-9 71335-1681 Bryant Ranch Prepack 60 TABLET in 1 BOTTLE (71335-1681-9) October 31, 2024
71335-1703-0 71335-1703 Bryant Ranch Prepack 40 TABLET in 1 BOTTLE (71335-1703-0) November 22, 2022
71335-1703-1 71335-1703 Bryant Ranch Prepack 20 TABLET in 1 BOTTLE (71335-1703-1) September 23, 2020
71335-1703-2 71335-1703 Bryant Ranch Prepack 30 TABLET in 1 BOTTLE (71335-1703-2) October 20, 2020
71335-1703-3 71335-1703 Bryant Ranch Prepack 14 TABLET in 1 BOTTLE (71335-1703-3) October 5, 2020
71335-1703-4 71335-1703 Bryant Ranch Prepack 56 TABLET in 1 BOTTLE (71335-1703-4) August 12, 2024
71335-1703-5 71335-1703 Bryant Ranch Prepack 21 TABLET in 1 BOTTLE (71335-1703-5) October 16, 2020
71335-1703-6 71335-1703 Bryant Ranch Prepack 4 TABLET in 1 BOTTLE (71335-1703-6) November 5, 2021
71335-1703-7 71335-1703 Bryant Ranch Prepack 28 TABLET in 1 BOTTLE (71335-1703-7) September 24, 2020
71335-1703-8 71335-1703 Bryant Ranch Prepack 100 TABLET in 1 BOTTLE (71335-1703-8) August 12, 2024
71335-1703-9 71335-1703 Bryant Ranch Prepack 60 TABLET in 1 BOTTLE (71335-1703-9) April 15, 2024
71335-1775-0 71335-1775 Bryant Ranch Prepack 7 TABLET in 1 BOTTLE (71335-1775-0) August 12, 2024
71335-1775-1 71335-1775 Bryant Ranch Prepack 21 TABLET in 1 BOTTLE (71335-1775-1) September 6, 2023
71335-1775-2 71335-1775 Bryant Ranch Prepack 30 TABLET in 1 BOTTLE (71335-1775-2) March 11, 2021
71335-1775-3 71335-1775 Bryant Ranch Prepack 20 TABLET in 1 BOTTLE (71335-1775-3) August 12, 2024
71335-1775-4 71335-1775 Bryant Ranch Prepack 60 TABLET in 1 BOTTLE (71335-1775-4) August 12, 2024
71335-1775-5 71335-1775 Bryant Ranch Prepack 28 TABLET in 1 BOTTLE (71335-1775-5) October 30, 2023
71335-1775-6 71335-1775 Bryant Ranch Prepack 14 TABLET in 1 BOTTLE (71335-1775-6) April 20, 2021
71335-1775-7 71335-1775 Bryant Ranch Prepack 40 TABLET in 1 BOTTLE (71335-1775-7) August 12, 2024
71335-1775-8 71335-1775 Bryant Ranch Prepack 42 TABLET in 1 BOTTLE (71335-1775-8) August 12, 2024
71335-1775-9 71335-1775 Bryant Ranch Prepack 56 TABLET in 1 BOTTLE (71335-1775-9) February 1, 2021
71335-1838-0 71335-1838 Bryant Ranch Prepack 7 TABLET in 1 BOTTLE (71335-1838-0) October 31, 2024
71335-1838-1 71335-1838 Bryant Ranch Prepack 21 TABLET in 1 BOTTLE (71335-1838-1) November 23, 2021
71335-1838-2 71335-1838 Bryant Ranch Prepack 30 TABLET in 1 BOTTLE (71335-1838-2) June 14, 2021
71335-1838-3 71335-1838 Bryant Ranch Prepack 20 TABLET in 1 BOTTLE (71335-1838-3) May 14, 2021
71335-1838-4 71335-1838 Bryant Ranch Prepack 60 TABLET in 1 BOTTLE (71335-1838-4) October 31, 2024
71335-1838-5 71335-1838 Bryant Ranch Prepack 28 TABLET in 1 BOTTLE (71335-1838-5) November 1, 2021
71335-1838-6 71335-1838 Bryant Ranch Prepack 14 TABLET in 1 BOTTLE (71335-1838-6) December 11, 2023
71335-1838-7 71335-1838 Bryant Ranch Prepack 40 TABLET in 1 BOTTLE (71335-1838-7) October 31, 2024
71335-1838-8 71335-1838 Bryant Ranch Prepack 42 TABLET in 1 BOTTLE (71335-1838-8) October 31, 2024
71335-1838-9 71335-1838 Bryant Ranch Prepack 56 TABLET in 1 BOTTLE (71335-1838-9) April 30, 2021
71335-1922-0 71335-1922 Bryant Ranch Prepack 40 TABLET in 1 BOTTLE (71335-1922-0) October 31, 2024
71335-1922-1 71335-1922 Bryant Ranch Prepack 20 TABLET in 1 BOTTLE (71335-1922-1) August 11, 2021
71335-1922-2 71335-1922 Bryant Ranch Prepack 30 TABLET in 1 BOTTLE (71335-1922-2) August 26, 2021
71335-1922-3 71335-1922 Bryant Ranch Prepack 14 TABLET in 1 BOTTLE (71335-1922-3) October 7, 2021
71335-1922-4 71335-1922 Bryant Ranch Prepack 56 TABLET in 1 BOTTLE (71335-1922-4) October 31, 2024
71335-1922-5 71335-1922 Bryant Ranch Prepack 21 TABLET in 1 BOTTLE (71335-1922-5) December 9, 2021
71335-1922-6 71335-1922 Bryant Ranch Prepack 4 TABLET in 1 BOTTLE (71335-1922-6) October 4, 2021
71335-1922-7 71335-1922 Bryant Ranch Prepack 28 TABLET in 1 BOTTLE (71335-1922-7) August 3, 2021
71335-1922-8 71335-1922 Bryant Ranch Prepack 100 TABLET in 1 BOTTLE (71335-1922-8) October 31, 2024
71335-1922-9 71335-1922 Bryant Ranch Prepack 60 TABLET in 1 BOTTLE (71335-1922-9) October 31, 2024
71335-2681-1 71335-2681 Bryant Ranch Prepack 14 TABLET in 1 BOTTLE (71335-2681-1) September 12, 2025
71335-2681-2 71335-2681 Bryant Ranch Prepack 3 TABLET in 1 BOTTLE (71335-2681-2) September 12, 2025
71335-2681-3 71335-2681 Bryant Ranch Prepack 9 TABLET in 1 BOTTLE (71335-2681-3) September 12, 2025
71335-2681-4 71335-2681 Bryant Ranch Prepack 10 TABLET in 1 BOTTLE (71335-2681-4) September 12, 2025
71335-2949-1 71335-2949 Bryant Ranch Prepack 56 TABLET in 1 BOTTLE (71335-2949-1) October 30, 2025
72162-2468-2 72162-2468 Bryant Ranch Prepack 56 TABLET in 1 BOTTLE (72162-2468-2) March 27, 2025
72162-2468-5 72162-2468 Bryant Ranch Prepack 500 TABLET in 1 BOTTLE (72162-2468-5) April 28, 2025
55154-2343-0 55154-2343 Cardinal Health 107, LLC 10 BLISTER PACK in 1 BAG (55154-2343-0) / 1 TABLET in 1 BLISTER PACK March 5, 2025
55154-8190-0 55154-8190 Cardinal Health 107, LLC 10 BLISTER PACK in 1 BAG (55154-8190-0) / 1 TABLET in 1 BLISTER PACK February 20, 2020
62135-795-90 62135-795 Chartwell RX, LLC 90 TABLET in 1 BOTTLE (62135-795-90) November 7, 2023
62135-796-90 62135-796 Chartwell RX, LLC 90 TABLET in 1 BOTTLE (62135-796-90) November 7, 2023
51407-372-01 51407-372 Golden State Medical Supply, Inc. 100 TABLET in 1 BOTTLE (51407-372-01) March 31, 2020
51407-372-05 51407-372 Golden State Medical Supply, Inc. 500 TABLET in 1 BOTTLE (51407-372-05) March 31, 2020
51407-376-01 51407-376 Golden State Medical Supply, Inc. 100 TABLET in 1 BOTTLE (51407-376-01) April 16, 2020
51407-376-05 51407-376 Golden State Medical Supply, Inc. 500 TABLET in 1 BOTTLE (51407-376-05) April 16, 2020
23155-651-01 23155-651 Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. 100 TABLET in 1 BOTTLE, PLASTIC (23155-651-01) November 29, 2017
23155-651-05 23155-651 Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. 500 TABLET in 1 BOTTLE, PLASTIC (23155-651-05) November 29, 2017
23155-652-01 23155-652 Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. 100 TABLET in 1 BOTTLE, PLASTIC (23155-652-01) November 29, 2017
23155-652-05 23155-652 Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. 500 TABLET in 1 BOTTLE, PLASTIC (23155-652-05) November 29, 2017
0904-7126-61 0904-7126 Major Pharmaceuticals 100 BLISTER PACK in 1 CARTON (0904-7126-61) / 1 TABLET in 1 BLISTER PACK November 29, 2017
0904-7156-61 0904-7156 Major Pharmaceuticals 100 BLISTER PACK in 1 CARTON (0904-7156-61) / 1 TABLET in 1 BLISTER PACK November 29, 2017
58657-739-01 58657-739 Method Pharmaceuticals LLC 100 TABLET in 1 BOTTLE (58657-739-01) January 4, 2025
58657-739-56 58657-739 Method Pharmaceuticals LLC 56 TABLET in 1 BOTTLE (58657-739-56) January 4, 2025
58657-933-01 58657-933 Method Pharmaceuticals LLC 100 BLISTER PACK in 1 CARTON (58657-933-01) / 1 TABLET in 1 BLISTER PACK (58657-933-10) July 1, 2025
58657-933-05 58657-933 Method Pharmaceuticals LLC 50 BLISTER PACK in 1 CARTON (58657-933-05) / 1 TABLET in 1 BLISTER PACK (58657-933-10) July 1, 2025
58657-934-01 58657-934 Method Pharmaceuticals LLC 100 BLISTER PACK in 1 CARTON (58657-934-01) / 1 TABLET in 1 BLISTER PACK (58657-934-10) July 1, 2025
58657-934-05 58657-934 Method Pharmaceuticals LLC 50 BLISTER PACK in 1 CARTON (58657-934-05) / 1 TABLET in 1 BLISTER PACK (58657-934-10) July 1, 2025
58657-939-01 58657-939 Method Pharmaceuticals LLC 100 BLISTER PACK in 1 CARTON (58657-939-01) / 1 TABLET in 1 BLISTER PACK (58657-939-10) July 1, 2025
58657-939-03 58657-939 Method Pharmaceuticals LLC 30 BLISTER PACK in 1 CARTON (58657-939-03) / 1 TABLET in 1 BLISTER PACK (58657-939-10) May 4, 2026
58657-939-05 58657-939 Method Pharmaceuticals LLC 50 BLISTER PACK in 1 CARTON (58657-939-05) / 1 TABLET in 1 BLISTER PACK (58657-939-10) July 1, 2025
51655-441-20 51655-441 Northwind Health Company, LLC 20 TABLET in 1 BOTTLE, PLASTIC (51655-441-20) January 19, 2023
51655-441-21 51655-441 Northwind Health Company, LLC 21 TABLET in 1 BOTTLE, PLASTIC (51655-441-21) November 30, 2022
51655-441-52 51655-441 Northwind Health Company, LLC 30 TABLET in 1 BOTTLE, PLASTIC (51655-441-52) June 27, 2023
51655-441-84 51655-441 Northwind Health Company, LLC 14 TABLET in 1 BOTTLE, PLASTIC (51655-441-84) January 11, 2023
51655-974-29 51655-974 Northwind Health Company, LLC 28 TABLET in 1 BOTTLE, PLASTIC (51655-974-29) April 3, 2023
51655-974-52 51655-974 Northwind Health Company, LLC 30 TABLET in 1 BOTTLE, PLASTIC (51655-974-52) February 28, 2023
82868-014-14 82868-014 Northwind Health Company, LLC 14 TABLET in 1 BOTTLE, PLASTIC (82868-014-14) September 28, 2023
82868-014-20 82868-014 Northwind Health Company, LLC 20 TABLET in 1 BOTTLE, PLASTIC (82868-014-20) August 12, 2024
82868-014-21 82868-014 Northwind Health Company, LLC 21 TABLET in 1 BOTTLE, PLASTIC (82868-014-21) February 5, 2024
82868-014-28 82868-014 Northwind Health Company, LLC 28 TABLET in 1 BOTTLE, PLASTIC (82868-014-28) October 4, 2023
82868-014-30 82868-014 Northwind Health Company, LLC 30 TABLET in 1 BOTTLE, PLASTIC (82868-014-30) November 30, 2023
68071-2251-6 68071-2251 NuCare Pharmaceuticals,Inc. 6 TABLET in 1 BOTTLE, PLASTIC (68071-2251-6) August 31, 2020
68071-2288-4 68071-2288 NuCare Pharmaceuticals,Inc. 4 TABLET in 1 BOTTLE (68071-2288-4) October 28, 2020
68071-2399-4 68071-2399 NuCare Pharmaceuticals,Inc. 4 TABLET in 1 BOTTLE (68071-2399-4) May 12, 2021
68071-2399-6 68071-2399 NuCare Pharmaceuticals,Inc. 6 TABLET in 1 BOTTLE (68071-2399-6) May 12, 2021
68071-2409-1 68071-2409 NuCare Pharmaceuticals,Inc. 4 TABLET in 1 BOTTLE (68071-2409-1) May 21, 2021
68071-2409-2 68071-2409 NuCare Pharmaceuticals,Inc. 21 TABLET in 1 BOTTLE (68071-2409-2) May 21, 2021
68071-2409-3 68071-2409 NuCare Pharmaceuticals,Inc. 30 TABLET in 1 BOTTLE (68071-2409-3) May 21, 2021
68071-2409-4 68071-2409 NuCare Pharmaceuticals,Inc. 14 TABLET in 1 BOTTLE (68071-2409-4) May 21, 2021
68071-2409-5 68071-2409 NuCare Pharmaceuticals,Inc. 40 TABLET in 1 BOTTLE (68071-2409-5) May 21, 2021
68071-2409-7 68071-2409 NuCare Pharmaceuticals,Inc. 20 TABLET in 1 BOTTLE (68071-2409-7) May 21, 2021
68071-2409-8 68071-2409 NuCare Pharmaceuticals,Inc. 28 TABLET in 1 BOTTLE (68071-2409-8) May 21, 2021
68071-2409-9 68071-2409 NuCare Pharmaceuticals,Inc. 90 TABLET in 1 BOTTLE (68071-2409-9) May 21, 2021
68071-5073-2 68071-5073 NuCare Pharmaceuticals,Inc. 21 TABLET in 1 BOTTLE (68071-5073-2) September 26, 2019
68071-5283-8 68071-5283 NuCare Pharmaceuticals,Inc. 28 TABLET in 1 BOTTLE, PLASTIC (68071-5283-8) June 18, 2020
72789-007-04 72789-007 PD-Rx Pharmaceuticals, Inc. 4 TABLET in 1 BOTTLE, PLASTIC (72789-007-04) December 16, 2019
72789-007-06 72789-007 PD-Rx Pharmaceuticals, Inc. 6 TABLET in 1 BOTTLE, PLASTIC (72789-007-06) October 30, 2023
72789-007-09 72789-007 PD-Rx Pharmaceuticals, Inc. 9 TABLET in 1 BOTTLE, PLASTIC (72789-007-09) October 9, 2019
72789-007-14 72789-007 PD-Rx Pharmaceuticals, Inc. 14 TABLET in 1 BOTTLE, PLASTIC (72789-007-14) September 13, 2019
72789-007-21 72789-007 PD-Rx Pharmaceuticals, Inc. 21 TABLET in 1 BOTTLE, PLASTIC (72789-007-21) September 26, 2019
72789-007-28 72789-007 PD-Rx Pharmaceuticals, Inc. 28 TABLET in 1 BOTTLE, PLASTIC (72789-007-28) June 4, 2020
72789-007-30 72789-007 PD-Rx Pharmaceuticals, Inc. 30 TABLET in 1 BOTTLE, PLASTIC (72789-007-30) November 21, 2019
72789-007-79 72789-007 PD-Rx Pharmaceuticals, Inc. 1 TABLET in 1 BOTTLE, PLASTIC (72789-007-79) November 7, 2019
72789-011-04 72789-011 PD-Rx Pharmaceuticals, Inc. 4 TABLET in 1 BOTTLE, PLASTIC (72789-011-04) August 20, 2019
72789-011-14 72789-011 PD-Rx Pharmaceuticals, Inc. 14 TABLET in 1 BOTTLE, PLASTIC (72789-011-14) January 13, 2020
72789-195-06 72789-195 PD-Rx Pharmaceuticals, Inc. 6 TABLET in 1 BOTTLE, PLASTIC (72789-195-06) October 29, 2021
72789-195-21 72789-195 PD-Rx Pharmaceuticals, Inc. 21 TABLET in 1 BOTTLE, PLASTIC (72789-195-21) June 30, 2021
72789-195-30 72789-195 PD-Rx Pharmaceuticals, Inc. 30 TABLET in 1 BOTTLE, PLASTIC (72789-195-30) June 30, 2021
68788-7815-1 68788-7815 Preferred Pharmaceuticals Inc. 14 TABLET in 1 BOTTLE (68788-7815-1) November 13, 2020
68788-7815-2 68788-7815 Preferred Pharmaceuticals Inc. 21 TABLET in 1 BOTTLE (68788-7815-2) November 13, 2020
68788-7815-3 68788-7815 Preferred Pharmaceuticals Inc. 30 TABLET in 1 BOTTLE (68788-7815-3) November 13, 2020
68788-7815-4 68788-7815 Preferred Pharmaceuticals Inc. 28 TABLET in 1 BOTTLE (68788-7815-4) November 13, 2020
68788-7815-5 68788-7815 Preferred Pharmaceuticals Inc. 56 TABLET in 1 BOTTLE (68788-7815-5) November 13, 2020
68788-7815-7 68788-7815 Preferred Pharmaceuticals Inc. 42 TABLET in 1 BOTTLE (68788-7815-7) November 13, 2020
63187-035-04 63187-035 Proficient Rx LP 4 TABLET in 1 BOTTLE (63187-035-04) December 14, 2021
63187-035-14 63187-035 Proficient Rx LP 14 TABLET in 1 BOTTLE (63187-035-14) November 1, 2018
63187-035-21 63187-035 Proficient Rx LP 21 TABLET in 1 BOTTLE (63187-035-21) November 1, 2018
63187-035-28 63187-035 Proficient Rx LP 28 TABLET in 1 BOTTLE (63187-035-28) August 23, 2024
63187-035-30 63187-035 Proficient Rx LP 30 TABLET in 1 BOTTLE (63187-035-30) November 1, 2018
63187-511-14 63187-511 Proficient Rx LP 14 TABLET in 1 BOTTLE (63187-511-14) August 12, 2021
63187-511-21 63187-511 Proficient Rx LP 21 TABLET in 1 BOTTLE (63187-511-21) August 12, 2021
63187-511-28 63187-511 Proficient Rx LP 28 TABLET in 1 BOTTLE (63187-511-28) August 12, 2021
63187-511-30 63187-511 Proficient Rx LP 30 TABLET in 1 BOTTLE (63187-511-30) August 12, 2021
63187-511-60 63187-511 Proficient Rx LP 60 TABLET in 1 BOTTLE (63187-511-60) August 12, 2021
63187-511-90 63187-511 Proficient Rx LP 90 TABLET in 1 BOTTLE (63187-511-90) August 12, 2021
70518-0013-0 70518-0013 REMEDYREPACK INC. 28 TABLET in 1 BOTTLE, PLASTIC (70518-0013-0) November 23, 2016
70518-1240-0 70518-1240 REMEDYREPACK INC. 4 TABLET in 1 BOTTLE, PLASTIC (70518-1240-0) June 1, 2018
70518-1240-1 70518-1240 REMEDYREPACK INC. 14 TABLET in 1 BOTTLE, PLASTIC (70518-1240-1) June 1, 2018
70518-1241-0 70518-1241 REMEDYREPACK INC. 14 TABLET in 1 BOTTLE, PLASTIC (70518-1241-0) June 1, 2018
70518-1241-2 70518-1241 REMEDYREPACK INC. 30 TABLET in 1 BOTTLE, PLASTIC (70518-1241-2) September 24, 2021
70518-2663-0 70518-2663 REMEDYREPACK INC. 4 TABLET in 1 BOTTLE, PLASTIC (70518-2663-0) March 30, 2020
70518-2663-4 70518-2663 REMEDYREPACK INC. 14 TABLET in 1 BOTTLE, PLASTIC (70518-2663-4) November 8, 2021
70518-2663-5 70518-2663 REMEDYREPACK INC. 4 TABLET in 1 BOTTLE, PLASTIC (70518-2663-5) August 31, 2022
70518-2663-7 70518-2663 REMEDYREPACK INC. 4 TABLET in 1 BOTTLE, PLASTIC (70518-2663-7) October 24, 2022
70518-3042-2 70518-3042 REMEDYREPACK INC. 28 TABLET in 1 BLISTER PACK (70518-3042-2) December 5, 2022
70518-3042-3 70518-3042 REMEDYREPACK INC. 28 TABLET in 1 BOTTLE, PLASTIC (70518-3042-3) March 25, 2025
70518-3110-5 70518-3110 REMEDYREPACK INC. 14 TABLET in 1 BOTTLE, PLASTIC (70518-3110-5) September 30, 2024
70518-3265-1 70518-3265 REMEDYREPACK INC. 4 TABLET in 1 BOTTLE, PLASTIC (70518-3265-1) February 10, 2022
70518-3265-2 70518-3265 REMEDYREPACK INC. 14 TABLET in 1 BOTTLE, PLASTIC (70518-3265-2) April 17, 2022
70518-3265-4 70518-3265 REMEDYREPACK INC. 20 TABLET in 1 BOTTLE, PLASTIC (70518-3265-4) October 3, 2025
70518-3265-5 70518-3265 REMEDYREPACK INC. 30 TABLET in 1 BLISTER PACK (70518-3265-5) December 20, 2025
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16571-665-01 16571-665 Rising Pharma Holdings, Inc. 100 TABLET in 1 BOTTLE (16571-665-01) May 29, 2015
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85766-024-01 85766-024 Sportpharm LLC 100 TABLET in 1 BOTTLE (85766-024-01) August 5, 2025
85766-024-05 85766-024 Sportpharm LLC 500 TABLET in 1 BOTTLE (85766-024-05) August 5, 2025
85766-024-14 85766-024 Sportpharm LLC 14 TABLET in 1 BOTTLE (85766-024-14) August 5, 2025
85766-024-20 85766-024 Sportpharm LLC 20 TABLET in 1 BOTTLE (85766-024-20) August 5, 2025
85766-024-30 85766-024 Sportpharm LLC 30 TABLET in 1 BOTTLE (85766-024-30) August 5, 2025
85766-024-50 85766-024 Sportpharm LLC 50 TABLET in 1 BOTTLE (85766-024-50) August 5, 2025
85766-024-60 85766-024 Sportpharm LLC 60 TABLET in 1 BOTTLE (85766-024-60) August 5, 2025
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72578-008-01 72578-008 Viona Pharmaceuticals Inc 100 TABLET in 1 BOTTLE (72578-008-01) February 23, 2019
72578-008-05 72578-008 Viona Pharmaceuticals Inc 500 TABLET in 1 BOTTLE (72578-008-05) February 23, 2019
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70771-1045-1 70771-1045 Zydus Lifesciences Limited 100 TABLET in 1 BOTTLE (70771-1045-1) February 23, 2019
70771-1045-5 70771-1045 Zydus Lifesciences Limited 500 TABLET in 1 BOTTLE (70771-1045-5) February 23, 2019
70771-1045-8 70771-1045 Zydus Lifesciences Limited 250 TABLET in 1 BOTTLE (70771-1045-8) February 23, 2019
70771-1046-1 70771-1046 Zydus Lifesciences Limited 100 TABLET in 1 BOTTLE (70771-1046-1) February 23, 2019
70771-1046-5 70771-1046 Zydus Lifesciences Limited 500 TABLET in 1 BOTTLE (70771-1046-5) February 23, 2019
70771-1046-7 70771-1046 Zydus Lifesciences Limited 50 TABLET in 1 BOTTLE (70771-1046-7) February 23, 2019
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Sources for this page

Every dataset that contributed a fact to this page.
Dataset Agency Used for
NDC Directory FDA Identity, ingredients, strengths, forms, routes, labelers, packages
Drugs@FDA FDA Application, sponsor, submissions, review documents, marketing status
Orange Book FDA Therapeutic equivalence codes, reference drug flags, patents, exclusivity
Drug Labeling FDA / NLM Prescribing information reproduced above
FAERS FDA Adverse event report counts
Drug Shortages FDA Supply availability

Generated September 25, 2026 · 13 sections on this page.